Managing the Antithrombotic Therapy After Percutaneous Coronary Intervention in Patients on Oral Anticoagulation.

Triple Antithrombotic Therapy: Risky but Sometimes Necessary Tratamiento antitrombótico combinado triple: arriesgado pero a veces necesario

Antithrombotic therapy is the fundamental treatment for various cardiovascular conditions, e.g. ischemic heart disease, atrial fibrillation (AF), and stroke to prevent thrombotic complications and death. Dual antiplatelet inhibition with acetylsalicylic acid (ASA) and a P2Y12 inhibitor has proven most effective in patients with recent myocardial infarction (MI) or after percutaneous coronary in...

Triple Antithrombotic Therapy in Atrial Fibrillation Patients With an Indication for Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A Case-Based Review of the Current Evidence.

The Woest Study: Is Now the Time to Update the Recommendations regarding the Antithrombotic Therapy in Patients with Indication for Oral Anticoagulation Undergoing Coronary Stent Implantation?

Triple therapy (TT) of warfarin, aspirin, and clopidogrel is currently recommended as the antithrombotic therapy for patients with an indication for oral anticoagulation (OAC) undergoing percutaneous coronary intervention (PCI) with stent implantation (PCI). While appearing to be the most effective regimen in preventing the combined incidence of stroke, death, myocardial infarction, re-revascul...

Antithrombotic management in patients with percutaneous coronary intervention requiring oral anticoagulation

The dynamic evolution of therapeutic options including the use of vitamin K antagonists (VKA), non-vitamin K oral anticoagulants (NOAC), more potent antiplatelet drugs as well as new generation drug-eluting stents could lead to the view that the current recommendations on the management of patients with percutaneous coronary intervention (PCI) requiring oral anticoagulation do not keep up with ...

Triple therapy for atrial fibrillation and percutaneous coronary intervention.

PURPOSE OF REVIEW Patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) require treatment with oral anticoagulation (OAC) and additional dual antiplatelet therapy with aspirin and clopidogrel (DAPT), i.e. triple therapy. However, triple therapy produces a high annual bleeding risk outweighing the benefits. To improve safety of antithrombotic treatment in these pa...